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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
23.64
Human Site:
S240
Identified Species:
40
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
S240
K
N
V
L
R
L
L
S
A
A
K
A
P
D
R
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
S467
K
N
V
L
R
L
L
S
A
A
K
A
P
D
R
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S318
K
N
V
V
K
L
L
S
S
R
R
T
Q
D
R
Dog
Lupus familis
XP_542019
1076
118222
S373
K
N
V
L
R
L
L
S
A
A
K
A
P
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
S243
K
N
V
L
R
L
L
S
G
A
K
A
P
D
R
Rat
Rattus norvegicus
Q63433
946
104449
S243
K
N
V
L
R
L
L
S
A
A
K
A
P
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G305
K
N
V
V
K
L
L
G
G
R
R
L
Q
D
R
Chicken
Gallus gallus
XP_422357
1013
114806
G271
K
N
V
M
K
L
L
G
S
G
K
V
T
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
G253
K
N
V
L
R
L
L
G
A
S
K
V
Q
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
E36
R
T
D
K
A
K
A
E
A
V
V
E
H
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
A109
D
Q
L
K
I
G
S
A
N
D
I
W
V
D
L
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
D167
V
R
I
M
G
C
Q
D
L
Q
E
M
I
P
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
A217
V
L
T
I
G
I
T
A
A
R
D
V
D
H
I
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T288
E
D
I
V
V
A
R
T
K
P
S
R
N
D
K
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
53.3
100
N.A.
93.3
100
N.A.
46.6
53.3
N.A.
66.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
80
100
N.A.
93.3
100
N.A.
66.6
73.3
N.A.
80
N.A.
13.3
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
15
50
36
0
36
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
0
0
8
0
8
8
0
8
79
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
8
0
22
15
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
15
8
8
8
0
0
0
0
8
0
8
0
8
% I
% Lys:
65
0
0
15
22
8
0
0
8
0
50
0
0
0
15
% K
% Leu:
0
8
8
43
0
65
65
0
8
0
0
8
0
0
8
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
65
0
0
0
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
36
8
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
8
0
0
22
0
0
% Q
% Arg:
8
8
0
0
43
0
8
0
0
22
15
8
0
0
58
% R
% Ser:
0
0
0
0
0
0
8
43
15
8
8
0
0
0
0
% S
% Thr:
0
8
8
0
0
0
8
8
0
0
0
8
8
8
0
% T
% Val:
15
0
65
22
8
0
0
0
0
8
8
22
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _